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Acta Obstet Gynecol Scand. 2005 Jan;84(1):54-7.

Sleep apnea and hormone replacement therapy: a pilot study and a literature review.

Author information

1
Department of Obstetrics and Gynecology, Falu Hospital, and Centre for Clinical Research Dalarna Falun, Sweden. jan.wesström@ltdalarna.se

Abstract

BACKGROUND:

Sleep apnea syndrome (SAS) is a common condition and a risk factor of cardiovascular and cerebrovascular diseases. The purpose of this pilot study was to investigate the effect of a gestagen (trimegeston) and estradiol hormone combination on perimenopausal and postmenopausal women with SAS.

METHODS:

Four postmenopausal and one perimenopausal women were studied by polysomnography before and after treatment with hormone replacement therapy (HRT).

RESULTS:

The subjects had a mean reduction of the severity of their sleep apnea by 75% measured by apnea/hypopnea index.

CONCLUSIONS:

HRT might be an alternative in the treatment of SAS.

[Indexed for MEDLINE]

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