Abstract
A 14-year-old girl is reported with recurrent, azithromycin-induced, acute interstitial nephritis. The second episode was more severe than the first; and although both were treated with intensive corticosteroid therapy, renal function remained impaired. Although most cases of antibiotic induced acute interstitial nephritis are benign and self-limited, some patients are at risk for permanent renal injury.
MeSH terms
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Acute Disease
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Adolescent
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Anti-Bacterial Agents / administration & dosage
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Anti-Bacterial Agents / adverse effects*
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Anti-Bacterial Agents / therapeutic use
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Azithromycin / administration & dosage
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Azithromycin / adverse effects*
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Female
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Glucocorticoids / therapeutic use
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Humans
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Methylprednisolone / therapeutic use
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Nephritis, Interstitial / chemically induced*
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Nephritis, Interstitial / drug therapy
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Prednisone / therapeutic use
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Recurrence
Substances
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Anti-Bacterial Agents
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Glucocorticoids
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Azithromycin
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Prednisone
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Methylprednisolone