Recurrent acute interstitial nephritis induced by azithromycin

Pediatr Infect Dis J. 2004 Oct;23(10):965-6. doi: 10.1097/01.inf.0000141753.41486.ff.

Abstract

A 14-year-old girl is reported with recurrent, azithromycin-induced, acute interstitial nephritis. The second episode was more severe than the first; and although both were treated with intensive corticosteroid therapy, renal function remained impaired. Although most cases of antibiotic induced acute interstitial nephritis are benign and self-limited, some patients are at risk for permanent renal injury.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use
  • Azithromycin / administration & dosage
  • Azithromycin / adverse effects*
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Methylprednisolone / therapeutic use
  • Nephritis, Interstitial / chemically induced*
  • Nephritis, Interstitial / drug therapy
  • Prednisone / therapeutic use
  • Recurrence

Substances

  • Anti-Bacterial Agents
  • Glucocorticoids
  • Azithromycin
  • Prednisone
  • Methylprednisolone