Format

Send to

Choose Destination
J Am Chem Soc. 2004 Dec 22;126(50):16316-7.

Recombinant HDL-like nanoparticles: a specific contrast agent for MRI of atherosclerotic plaques.

Author information

1
Imaging Science Laboratories, Department of Radiology, Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York, USA.

Abstract

A new contrast agent for MRI based on recombinant HDL-like nanoparticles has been prepared. It shows a great potential as a contrast agent for atherosclerotic plaques in a relative short time (24 h post-injection) as it is selective for the plaques and is an endogenous molecule. It also can distinguish between different types of plaques as the enhancement obtained is different, depending on plaque composition.

PMID:
15600321
DOI:
10.1021/ja044911a
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Chemical Society
Loading ...
Support Center