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Microbes Infect. 2004 Dec;6(15):1368-73.

Integration of Toll-like receptor and phagocytic signaling for tailored immunity.

Author information

1
Institute for Systems Biology, 1441 N. 34th Street, Seattle, WA 98103, USA. dunderhill@systemsbiology.org

Abstract

Toll-like receptors (TLRs) are recruited to phagosomes and sample the contents of the compartment for microbial products. In this review, we discuss the relationship between phagocytosis and TLRs from two additional perspectives: first, TLR signaling modulates phagocytosis; second, phagocytosis modulates the consequences of TLR activation.

PMID:
15596122
DOI:
10.1016/j.micinf.2004.08.016
[Indexed for MEDLINE]

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