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Microbes Infect. 2004 Dec;6(15):1356-60.

Viruses and Toll-like receptors.

Author information

1
Department of Medicine, University of Massachusetts Medical School, 364 Plantation Street, LRB 228, Worcester, MA 01605, USA. robert.finberg@umassmed.edu

Abstract

Production of inflammatory cytokines and type I interferons by mammalian cells is mediated through virus-specific activation of Toll-like receptors (TLRs). Known roles for different TLRs and speculation as to their roles in viral pathogenesis and immunity are discussed in this review.

PMID:
15596120
DOI:
10.1016/j.micinf.2004.08.013
[Indexed for MEDLINE]

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