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Curr Opin Neurobiol. 2004 Dec;14(6):769-76.

Reward representations and reward-related learning in the human brain: insights from neuroimaging.

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1
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London WC1N 3BG, UK. jdoherty@hss.caltech.edu

Abstract

This review outlines recent findings from human neuroimaging concerning the role of a highly interconnected network of brain areas including orbital and medial prefrontal cortex, amygdala, striatum and dopaminergic mid-brain in reward processing. Distinct reward-related functions can be attributed to different components of this network. Orbitofrontal cortex is involved in coding stimulus reward value and in concert with the amygdala and ventral striatum is implicated in representing predicted future reward. Such representations can be used to guide action selection for reward, a process that depends, at least in part, on orbital and medial prefrontal cortex as well as dorsal striatum.

PMID:
15582382
DOI:
10.1016/j.conb.2004.10.016
[Indexed for MEDLINE]
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