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Curr Opin Neurobiol. 2004 Dec;14(6):675-84.

Persistent neural activity: prevalence and mechanisms.

Author information

1
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA. gmajor@princeton.edu

Abstract

Persistent neural activity refers to a sustained change in action potential discharge that long outlasts a stimulus. It is found in a diverse set of brain regions and organisms and several in vitro systems, suggesting that it can be considered a universal form of circuit dynamics that can be used as a mechanism for short-term storage and accumulation of sensory or motor information. Both single cell and network mechanisms are likely to co-operate in generating persistent activity in many brain areas.

PMID:
15582368
DOI:
10.1016/j.conb.2004.10.017
[Indexed for MEDLINE]

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