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J Pediatr. 2004 Dec;145(6):856-7.

Thalidomide for severe systemic onset juvenile rheumatoid arthritis: A multicenter study.

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1
Division of Pediatric Rheumatology, Hospital for Special Surgery, and the Department of Pediatrics, Sanford Weill Medical College of Cornell University, New York, New York, USA.

Abstract

Thirteen children with difficult systemic onset juvenile rheumatoid arthritis were treated with thalidomide. At 6 months, 11 of the 13 were able to reduce their use of prednisone ( P < .002), with a concurrent improvement in erythrocyte sedimentation rate ( P < .0001) and an increase in hemoglobin level ( P < 0.005). Juvenile rheumatoid arthritis improvement scores >/=50% were obtained by 10 of the 13 children.

PMID:
15580219
DOI:
10.1016/j.jpeds.2004.08.020
[Indexed for MEDLINE]
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