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Vaccine. 1992;10(3):142-4.

Relative efficacy of two acellular pertussis vaccines during three years of passive surveillance.

Author information

1
Department of Paediatrics, Sachs' Children's Hospital, Karolinska Institute, Stockholm, Sweden.

Abstract

Prolonged unblinded passive surveillance of the trial cohort from the Swedish 1986-87 pertussis vaccine efficacy trial indicates that a two-component vaccine, containing pertussis toxoid and filamentous haemagglutinin, provided better long-term protection against pertussis than a monocomponent pertussis toxoid vaccine. The relative risk (RR) for culture-confirmed pertussis was 1.5 (95% confidence interval (CI) 1.0-2.4), and RR for pertussis according to parents' diagnoses was also 1.5 (95% CI 1.1-2.1), for the monocomponent vaccine compared with the two-component vaccine.

PMID:
1557928
DOI:
10.1016/0264-410x(92)90002-2
[Indexed for MEDLINE]

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