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Genet Vaccines Ther. 2004 Dec 3;2(1):17.

DNA vaccines: designing strategies against parasitic infections.

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Institute of Parasitology of McGill University, Macdonald Campus, 21,111 Lakeshore Road, Ste, Anne de Bellevue, Quebec, Canada, H9X 3V9.


The complexity of parasitic infections requires novel approaches to vaccine design. The versatility of DNA vaccination provides new perspectives. This review discusses the use of prime-boost immunizations, genetic adjuvants, multivalent vaccines and codon optimization for optimal DNA vaccine design against parasites.

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