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Genet Vaccines Ther. 2004 Dec 3;2(1):17.

DNA vaccines: designing strategies against parasitic infections.

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1
Institute of Parasitology of McGill University, Macdonald Campus, 21,111 Lakeshore Road, Ste, Anne de Bellevue, Quebec, Canada, H9X 3V9. kris.chadee@mcgill.ca.

Abstract

The complexity of parasitic infections requires novel approaches to vaccine design. The versatility of DNA vaccination provides new perspectives. This review discusses the use of prime-boost immunizations, genetic adjuvants, multivalent vaccines and codon optimization for optimal DNA vaccine design against parasites.

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