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Clin Calcium. 2004 Oct;14(10):129-32.

[Treatment of the keratinizing skin disorder, psoriasis, by topical vitamin D3].

[Article in Japanese]

Author information

1
Department of Dermatology, Asahikawa Medical College.

Abstract

The active vitamin D(3) regulates proliferation and differentiation of epidermal keratinocytes. Although topical application of steroid has been principal therapy for psoriasis, there occurs some side effects such as skin atropy, telangiectasis, and purpura. Recently topical vitamin D(3), tacalcitol, calcipotriol, and maxacalcitol, which avoid these side effects, are widely used for psoriasis. In this review, we discussed the mechanism, effect, and side effect of topical vitamin D(3) for psoriasis.

PMID:
15577145
DOI:
CliCa041015991602
[Indexed for MEDLINE]

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