Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Calcium. 2004 Jul;14(7):72-5.

[Relationship between gene transfer and cartilage tissue engineering].

[Article in Japanese]

Author information

  • 1Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo.

Abstract

Injury to the articular cartilage occurs under various pathological conditions such as trauma, inflammation and aging and is followed by osteoarthritic changes of the affected joints. Recently, some studies have revealed that enough chondrogenic proliferation was required using some factors such as TGF-beta and BMPs. We, also, have reported that synovial tissues include multipotent mesenchymal stem cells, which can differentiate into chondrocytes. These results suggest that not only are synovial cells a good therapeutic target of inflammatory joint diseases, but also can be utilized for tissue engineering of cartilage.

PMID:
15577079
DOI:
CliCa040710921095
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center