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Neurosurgery. 2004 Dec;55(6):1430.

Aggressive intramedullary melanotic schwannoma: case report.

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1
Brain Tumor Research Center, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.

Abstract

OBJECTIVE AND IMPORTANCE:

Intramedullary melanotic schwannomas are very rare lesions; only four cases have been reported previously. We describe a patient with an intramedullary melanotic schwannoma that had a more aggressive course than those reported in the literature, and we review the theories regarding the cause of these lesions.

CLINICAL PRESENTATION:

A 35-year-old man presented with neck stiffness and paraesthesia extending down his right arm upon neck extension. A magnetic resonance imaging scan revealed an intramedullary lesion extending from C4 to C5.

INTERVENTION:

Gross total resection of the mass was performed, and pathological characteristics were consistent with a melanotic schwannoma. Two years after resection the tumor recurred, and the patient was treated with radiation therapy. The tumor progressed 2 years after radiotherapy, and at repeat resection, multiple pigmented foci were present on the surface of the spinal cord and dura consistent with metastatic seeding.

CONCLUSION:

In a patient with intramedullary melanotic schwannoma with an unusually aggressive course, careful follow-up may be essential.

PMID:
15574225
[Indexed for MEDLINE]

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