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Nat Rev Mol Cell Biol. 2004 Dec;5(12):983-97.

Meiosis: cell-cycle controls shuffle and deal.

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1
Center for Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, E17-233, 40 Ames Street, Cambridge, Massachusetts 02139, USA.

Erratum in

  • Nat Rev Mol Cell Biol. 2005 Oct;6(10):818.

Abstract

Meiosis is the type of cell division that gives rise to eggs and sperm. Errors in the execution of this process can result in the generation of aneuploid gametes, which are associated with birth defects and infertility in humans. Here, we review recent findings on how cell-cycle controls ensure the coordination of meiotic events, with a particular focus on the segregation of chromosomes.

PMID:
15573136
DOI:
10.1038/nrm1526
[Indexed for MEDLINE]
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