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Bioinformatics. 2005 May 1;21(9):2112-3. Epub 2004 Nov 30.

MACAT--microarray chromosome analysis tool.

Author information

1
Freie Universitaet Berlin, Bioinformatics programme and Max Planck Institute for Molecular Genetics, Germany.

Abstract

By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable parts of specific chromosomes. We have implemented a statistical approach for identifying significantly differentially expressed chromosome regions. We demonstrate the applicability of the approach on a publicly available data set on acute lymphocytic leukemia.

AVAILABILITY:

The R-package MACAT can be obtained from http://www.compdiag.molgen.mpg.de/software/macat.shtml

SUPPLEMENTARY INFORMATION:

http://www.compdiag.molgen.mpg.de/software/macat.shtml.

PMID:
15572464
DOI:
10.1093/bioinformatics/bti183
[Indexed for MEDLINE]

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