Format

Send to

Choose Destination
Nature. 1992 Apr 2;356(6368):397-400.

Social controls on cell survival and cell death.

Author information

1
Department of Biology, University College London, UK.

Abstract

Programmed cell death occurs in most animal tissues at some stage of their development, but the molecular mechanism by which it is executed is unknown. For some mammalian cells, programmed death seems to occur by default unless suppressed by signals from other cells. Such dependence on specific survival signals provides a simple way to eliminate misplaced cells, for regulating cell numbers and, perhaps, for selecting the fittest cells. But how general is this dependence on survival signals?

PMID:
1557121
DOI:
10.1038/356397a0
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center