Format

Send to

Choose Destination
Am J Public Health. 2004 Dec;94(12):2149-54.

Socioeconomic position and hormone replacement therapy use: explaining the discrepancy in evidence from observational and randomized controlled trials.

Author information

1
Department of Social Medicine, University of Bristol, Bristol BS7 8QA, UK. d.a.lawlor@bristol.ac.uk

Abstract

OBJECTIVES:

We assessed the association between life-course socioeconomic status or position (SEP) and hormone replacement therapy (HRT).

METHODS:

We conducted a cross-sectional analysis of 4286 women aged 60 to 79 years.

RESULTS:

Women experiencing adverse socioeconomic circumstances across the life course were less likely to have used HRT. The associations of childhood socioeconomic measures with HRT use were independent of adult SEP, behavioral risk factors, and physiological risk factors for heart disease.

CONCLUSIONS:

SEP from across the life course is associated with HRT use. Because the association between early life SEP and HRT is not fully explained by adult risk factors, residual confounding (which is not captured by adjustment for adult variables only) may explain some of the disparity between observational studies and randomized controlled trials in this area.

PMID:
15569967
PMCID:
PMC1448605
DOI:
10.2105/ajph.94.12.2149
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Atypon Icon for PubMed Central
Loading ...
Support Center