Format

Send to

Choose Destination
See comment in PubMed Commons below
Int J Dev Biol. 2004;48(8-9):935-45.

A moving wave patterns the cone photoreceptor mosaic array in the zebrafish retina.

Author information

1
Department of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-0616, USA. praymond@umich.edu

Abstract

In this paper, we describe the embryonic origin and patterning of the planar mosaic array of cone photoreceptor spectral subtypes in the zebrafish retina. A discussion of possible molecular mechanisms that might generate the cone mosaic array considers but discards a model that accounts for formation of neuronal mosaics in the inner retina and discusses limitations of mathematical simulations that reproduce the zebrafish cone mosaic pattern. The formation and organization of photoreceptors in the ommatidia of the compound eye of Drosophila is compared with similar features in the developing zebrafish cone mosaic, and a model is proposed that invokes spatiotemporally coordinated cell-cell interactions among cone progenitors to determine the identity and positioning of cone spectral subtypes.

PMID:
15558484
DOI:
10.1387/ijdb.041873pr
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for The International Journal of Developmental Biology
    Loading ...
    Support Center