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Eur J Pediatr. 2005 Mar;164(3):141-5. Epub 2004 Nov 19.

Plasma aldosterone levels in the 1st week of life in infants of less than 30 weeks gestation.

Author information

  • 1Newborn Intensive Care Unit, Waikato Hospital, Private Bag 3200, Hamilton, New Zealand. bourchid@waikatodhb.govt.nz

Abstract

Plasma aldosterone levels were measured in 50 infants of less than 30 weeks gestation at 24 h (D1) and 7 days (D7). The relationship between the plasma aldosterone level and a number of clinical and biochemical variables was explored. Plasma aldosterone levels ranged from 1000 to 30000 pmol/l and were inversely correlated with the severity of illness (D1 or D7), serum sodium (D7) and 24 h sodium intake (D1). No correlation with the serum potassium level was noted.

CONCLUSION:

Plasma aldosterone levels in this extremely premature cohort were significantly greater than those reported in more mature infants. Important determinants were severity of illness and sodium homeostasis.

[PubMed - indexed for MEDLINE]
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