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Infect Immun. 2004 Dec;72(12):7326-9.

Two tonB systems function in iron transport in Vibrio anguillarum, but only one is essential for virulence.

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  • 1Department of Molecular Microbiology and Immunology, Oregon Health & Science University, SW Sam Jackson Park Road, Portland, OR 97239, USA.

Abstract

We have identified two functional tonB systems in the marine fish pathogen Vibrio anguillarum, tonB1 and tonB2. Each of the tonB genes is transcribed in an operon with the cognate exbB and exbD genes in response to iron limitation. Only tonB2 is essential for transport of ferric anguibactin and virulence.

PMID:
15557661
PMCID:
PMC529167
DOI:
10.1128/IAI.72.12.7326-7329.2004
[PubMed - indexed for MEDLINE]
Free PMC Article
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