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Gan To Kagaku Ryoho. 2004 Oct;31(11):1646-8.

[Long-term prognosis of hepatocellular carcinoma patients treated with adoptive immunotherapy].

[Article in Japanese]

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  • 1Cancer Immuno-Chemotherapy Center, Iseikai Hospital.


Adoptive immunotherapy was performed for patients with multiple hepatocellular carcinoma (HCC) using LAK cells via the hepatic arterial catheter. One case study: A 45-year-old male patient was performed an absolute-non-cure operation. The operation was a success. However, some residual tumors remained in the liver. After the operation, adoptive immunotherapy was performed for 7 times in 5 weeks. The total inoculated LAK cells were 6.9x10(9). After the adoptive immunotherapy, no residual tumors were detected in the liver. He survived for 7 years in remission. Our results show that adoptive immunotherapy with LAK cells is useful and effective for patients with multiple HCC.

[PubMed - indexed for MEDLINE]
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