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Virus Genes. 2004 Dec;29(3):317-9.

Translation of varicella-zoster virus genes during human ganglionic latency.

Author information

1
Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Scotland, UK.

Abstract

Immunohistochemical analysis of fixed tissue sections of human trigeminal ganglia (TG) and dorsal root ganglia (DRG) revealed the neuronal expression of proteins encoded by Varicella-zoster virus (VZV) genes 21, 29, 62 and 63. These proteins were detected mainly in the neuronal cytoplasm, are likely to be present in low abundance during VZV latency, and mirror the profile of VZV gene transcription.

PMID:
15550771
DOI:
10.1007/s11262-004-7434-z
[Indexed for MEDLINE]

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