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Eur Arch Psychiatry Clin Neurosci. 2004 Dec;254(6):372-9. Epub 2004 Nov 12.

Electroconvulsive therapy for the treatment of clozapine nonresponders suffering from schizophrenia--an open label study.

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1
GGZ Delfland, St Jorisweg 2, 2612 GA Delft, The Netherlands. k.kho@ggz-delfland.nl

Abstract

OBJECTIVE:

This open label study describes the efficacy of electroconvulsive therapy (ECT) as adjunctive treatment in clozapine nonresponders suffering from schizophrenia.

METHOD:

The results of clozapine and ECT treatment in 11 clozapine nonresponders suffering from schizophrenia are reported in terms of remission and relapse.

RESULTS:

Eight patients had a remission with this combination treatment. After remission of symptoms five patients had a relapse. Three of the five patients who relapsed had a second successful ECT course and remained well with maintenance ECT and clozapine. No evidence for adverse effects was found.

CONCLUSION:

Adjunctive ECT can be efficacious in clozapine nonresponders suffering from schizophrenia.

PMID:
15538604
DOI:
10.1007/s00406-004-0517-y
[Indexed for MEDLINE]
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