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Skinmed. 2004 Nov-Dec;3(6):310-6.

Protective effects of oral antioxidants on skin and eye function.

Author information

1
Department of Dermatology, II University of Naples, Naples, Italy. morganti@iscd.it.

Abstract

BACKGROUND:

Antioxidants applied topically and/or taken systemically may play an important role in counteracting the oxidative injury to lipids and proteins on the skin and eye that are provoked by radical oxygen species.

OBJECTIVE:

The aim of the study was to control photoprotective activity of the skin and eye through the use of oral antioxidants in 50 smoker volunteers (10 cigarettes/d) aged between 25-36 years and affected by dry skin.

METHODS:

Oxidative stress was assessed by a randomized double-blind study, and the ROS-Meter System (Dermotech, Rome, Italy). Global visual function was determined by the use of different visual surveillance tests.

RESULTS:

A 40% decrease of oxidative stress in blood serum was verified, with a clear relationship between global visual function and the oral intake of an oxygenated carotenoid (lutein).

CONCLUSIONS:

Carotenoids used as nutritional supplements seem to play an interesting photoprotective role for both skin and eyes, eventually increasing the activity of topical sunscreens.

[Indexed for MEDLINE]

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