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J Stud Alcohol. 2004 Sep;65(5):672-6.

Discriminating between substance-induced and independent depressive episodes in alcohol dependent patients.

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1
Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island 02903, USA. Susan_Ramsey@Brown.edu

Abstract

OBJECTIVE:

The purpose of this study is to examine the accuracy with which the depressive episodes of alcoholics undergoing treatment are classified as substance-induced depression (SID) or independent major depressive disorder (MDD).

METHOD:

Participants were 95 patients (64 men) undergoing partial hospital treatment for alcohol dependence. Affective disorders were assessed at baseline and 6 weeks, 3 months, 6 months and 12 months later.

RESULTS:

Over one quarter of the depressive episodes originally diagnosed as SID were reclassified as MDD during the 1-year follow-up, due to a continuation of the depressive episode despite a period of prolonged abstinence from alcohol and drugs. Both history of MDD and lower levels of alcohol dependence were associated with diagnostic change from SID to MDD.

CONCLUSIONS:

These findings support the diagnostic complexity of these two types of depressive disorders and point to clinical features that may differentiate them.

PMID:
15536779
[Indexed for MEDLINE]
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