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Am J Ophthalmol. 2004 Nov;138(5):871-2.

Visibility of lamina cribrosa pores and open-angle glaucoma.

Author information

1
University of Sydney Department of Ophthalmology, Westmead Millennium Institute, Westmead Hospital, Westmead, Australia. phealey@glaucoma.net.au

Abstract

PURPOSE:

To determine prevalence and associations of visible lamina cribrosa pores in an older population and assess whether this feature is associated with open-angle glaucoma (OAG).

DESIGN:

Case-control study nested within a large, population-based cross-sectional study.

METHODS:

The Blue Mountains Eye Study examined 3654 persons (82.4% of permanent residents of a defined area) aged over 48 years. Stereo optic disk photographs were taken and graded reliably in a masked fashion.

RESULTS:

Lamina pore visibility was associated with larger vertical cup-disk ratio and optic disk diameter, hyperopic refraction, and male gender. Pores were slightly less visible with increasing age. They were visible in 70.8% of subjects with open-angle glaucoma but in only 29.3% of normals. This strong association disappeared after adjusting for other variables.

CONCLUSION:

Lamina cribrosa pores are commonly visible in glaucoma subjects and less commonly in normals. This association, however, is almost entirely because of an increased visibility associated with larger vertical cup-disk ratio and optic disk size.

PMID:
15531331
DOI:
10.1016/j.ajo.2004.05.058
[Indexed for MEDLINE]

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