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Acta Paediatr. 2004 Nov;93(11):1486-90.

The value of Bilicheck as a screening tool for neonatal jaundice in term and near-term babies.

Author information

1
Neonatal Unit, Liverpool Women's Hospital, Liverpool, UK.

Abstract

AIMS:

To determine the accuracy of Bilicheck in assessing serum bilirubin. To evaluate the effectiveness of Bilicheck as a screening device in a population of jaundiced term and near-term babies.

METHODS:

Prospective evaluation of paired Bilicheck measurements and serum bilirubin in 300 babies.

RESULTS:

There was a strong correlation between Bilicheck and serum bilirubin. The mean difference between Bilicheck and serum bilirubin was -10.7 micromol/l, but the 95% limits of agreement were wide at -80 micromol/l to +60 micromol/l. Bilicheck identified significant jaundice (serum bilirubin above 250 micromol/l) with a sensitivity (95% confidence interval) of 91% (88% to 94%) and specificity of 66% (60% to 71%). The area under the receiver operator characteristic curve was 0.85. There were five false negatives, all of whom had a serum bilirubin below 300 micromol/l. If Bilicheck had been used as a screening device, there would have been a 55% decrease in blood samples taken in these babies.

CONCLUSION:

Bilicheck cannot be used to measure serum bilirubin in term and near-term babies with jaundice, but is an effective screening method, which can be used to safely reduce the number of blood tests in these babies.

PMID:
15513577
DOI:
10.1080/08035250410033042
[Indexed for MEDLINE]

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