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Cancer Invest. 1992;10(2):129-33.

Synchronous double malignancy: adenocarcinoma of lung and malignant astrocytoma induced by asbestos exposure.

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Department of Clinical Investigation, Kure Kyosai Hospital, Nishichuo Kure, Japan.


A 54-year-old male died of cerebellar herniation induced by brain tumor. Radiological examination of this case showed two separate tumorous lesions in the brain and lung. Autopsy proved malignant astrocytoma in the brain and coincidental alveolar cell carcinoma in the lung. He had a history of asbestos exposure for 8 years doing piping work in a shipyard. Furthermore, we detected a large number of asbestos bodies in the lung and one asbestos body in the brain. Therefore, this rare case of double cancer (malignant astrocytoma and lung cancer) might have been induced by asbestos exposure.

[Indexed for MEDLINE]

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