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Sex Transm Dis. 2004 Nov;31(11):659-64.

Targeted screening for Trichomonas vaginalis with culture using a two-step method in women presenting for STD evaluation.

Author information

  • 1Department of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, 27599-7030, USA. Heidi_Swygard@med.unc.edu

Abstract

OBJECTIVES:

Trichomonas vaginalis is the most common nonviral sexually transmitted pathogen. Wet mount microscopy performs poorly compared with culture; however, universal screening using culture would be cost-prohibitive.

GOAL:

The goal of this study was to develop a predictive model for wet mount-negative women who may benefit from targeted use of culture for T. vaginalis detection.

STUDY:

Women presenting for sexually transmitted disease evaluation were prospectively screened for trichomoniasis using wet mount and culture. Multivariate logistic regression was used to identify predictors of culture-proven trichomoniasis among wet mount-negative women.

RESULTS:

A total of 2194 women were screened for trichomoniasis; overall, the prevalence of T. vaginalis was 17.5%. Three predictors (any drug use, contact to trichomoniasis, and African-American race) provided the most specific model (100%); any 1 predictor, the most sensitive model (97.8%).

CONCLUSIONS:

Given the public health impact of trichomoniasis, we recommend using any 1 of 3 predictors to identify women who would benefit from targeted culture for T. vaginalis.

PMID:
15502673
[PubMed - indexed for MEDLINE]
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