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Nutr Rev. 2004 Sep;62(9):354-9.

Hypovitaminosis D-induced pain.

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1
Department of Internal Medicine, Loyola University Medical Center, Maywood, IL 60153, USA.

Abstract

Vitamin D deficiency is a problem of considerable magnitude that has reemerged as a major public health issue in the United States and several other developed countries. Vitamin D plays a crucial role in calcium homeostasis in the body. Hypovitaminosis D leads to osteomalacia and increased risk of fractures, especially in the elderly. Preliminary research suggests that vitamin D can prevent certain types of cancer and autoimmune diseases. A recent large study has shown the association between severe hypovitaminosis D and persistent, non-specific musculoskeletal pain, further suggesting that patients with no apparent cause of pain should be assessed and possibly treated for vitamin D deficiency.

PMID:
15497769
[Indexed for MEDLINE]
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