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World J Gastroenterol. 2004 Nov 15;10(22):3342-4.

Helicobacter pylori seroprevalence in patients with lung cancer.

Author information

1
9th Department of Pulmonary Medicine, SOTIRIA Chest Diseases Hospital, 152 Mesogion Street, PO Box 11527, Athens, Greece. roumar26@yahoo.com

Abstract

AIM:

To assess Helicobacter pylori (H pylori) seroprevalence in a cohort of Greek patients with lung cancer.

METHODS:

Seventy-two lung cancer patients (55 males and 17 females, aged 58.2+/-11.7 years) and 68, age and gender-matched, control subjects were enrolled. All subjects underwent an enzyme-linked immunosorbent assay IgG serologic test for H pylori diagnosis.

RESULTS:

A correlation between age and H pylori IgG level was detected for both lung cancer patients (r = 0.42, P = 0.004) and controls (r = 0.44, P = 0.004). Seropositivity for H pylori did not differ significantly between patients with lung cancer and controls (61.1% vs 55.9%, P>0.05). Concerning the mean serum concentration of IgG antibodies against H pylori, no significant difference between the two groups was detected (32.6+/-19.1 vs 27.4+/-18.3 U/mL, P>0.05).

CONCLUSION:

No significant association between H pylori infection and lung cancer was found.

PMID:
15484314
PMCID:
PMC4572309
DOI:
10.3748/wjg.v10.i22.3342
[Indexed for MEDLINE]
Free PMC Article

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