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Fertil Steril. 2004 Oct;82(4):968-9.

A pilot study of the relationship between selective serotonin reuptake inhibitors and in vitro fertilization outcome.

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Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA.


In a retrospective chart review study women taking selective serotonin reuptake inhibitors antidepressants were compared with a matched comparison group to determine whether there were any differences in IVF outcome-related variables. There were no significant differences between the groups in peak E(2), number of oocytes retrieved, number of oocytes fertilized, percentage of 8-cell or blastocysts developed, day of transfer, or initial hCG values; however, 40% of women taking selective serotonin reuptake inhibitors had ongoing pregnancies compared to 51% of women not taking selective serotonin reuptake inhibitors.

[Indexed for MEDLINE]

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