Multiple chondromatous hamartomas of the lung are extremely rare. We report a case of a 78 year-old man admitted to our service for a neurological syndrome associated with cerebral cancer. Chest-X-ray and computed tomography revealed multiple and bilateral pulmonary nodules. A metastatic carcinoma was initially taken into account but, in the light of natural history of the disease, clinical examination and CT-scan characteristics of the lesions, we formulated the final diagnosis of multiple bilateral chondromatous hamartomas of the lung.