Format

Send to

Choose Destination
Eur J Vasc Endovasc Surg. 2004 Nov;28(5):520-5.

Early post-operative glucose levels are an independent risk factor for infection after peripheral vascular surgery. A retrospective study.

Author information

1
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands. t.m.vriesendorp@amc.uva.nl

Abstract

OBJECTIVE:

To evaluate whether hyperglycaemia in the first 48 h after infrainguinal vascular surgery is a risk factor for post-operative infection, independent from factors associated with insulin resistance and surgical stress.

DESIGN:

Retrospective cohort study.

PATIENTS AND METHODS:

Patients who underwent infrainguinal vascular surgery in our hospital between March 1998 and March 2003 were included. Glucose values until 48 h after surgery were retrieved from laboratory reports. Post-operative infections, treated with antibiotics, during hospital stay were scored until 30 days after surgery. Data were analysed with univariate and multivariate logistic regression analyses.

RESULTS:

At least one post-operative glucose value was retrieved for 211/275 (77%) patients. The incidence of post-operative infections was 84/275 (31%). When corrected for factors associated with insulin resistance and surgical stress, post-operative glucose levels were found to be an independent risk factor for post-operative infections (odds ratio top quartile versus lowest quartile: 5.1; 95% confidence interval: 1.6-17.1; P=0.007).

CONCLUSION:

Post-operative glucose levels appear to be an independent risk factor for infections after infrainguinal vascular surgery. This finding requires confirmation in a prospective study.

PMID:
15465374
DOI:
10.1016/j.ejvs.2004.08.006
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center