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J Cyst Fibros. 2004 Aug;3 Suppl 2:183-90.

Animal models of cystic fibrosis.

Author information

1
Department of Cell Biology, Erasmus Medical Centre, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. b.scholte@erasmusmc.nl

Abstract

Animal models of cystic fibrosis, in particular several different mutant mouse strains obtained by homologous recombination, have contributed considerably to our understanding of CF pathology. In this review, we describe and compare the main phenotypic features of these models. Recent and possible future developments in this field are discussed.

PMID:
15463956
DOI:
10.1016/j.jcf.2004.05.039
[Indexed for MEDLINE]
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