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Nat Rev Mol Cell Biol. 2004 Oct;5(10):855-61.

Imaging gene expression in single living cells.

Author information

1
Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

Abstract

Technical advances in the field of live-cell imaging have introduced the cell biologist to a new, dynamic, subcellular world. The static world of molecules in fixed cells has now been extended to the time dimension. This allows the visualization and quantification of gene expression and intracellular trafficking events of the studied molecules and the associated enzymatic processes in individual cells, in real time.

PMID:
15459666
PMCID:
PMC4942131
DOI:
10.1038/nrm1494
[Indexed for MEDLINE]
Free PMC Article

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