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Anal Quant Cytol Histol. 2004 Aug;26(4):230-2.

Utility of mean nuclear volume in predicting disease-free survival in locally advanced invasive cervical squamous cell carcinoma.

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1
Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Abstract

OBJECTIVE:

To evaluate mean nuclear volume (MNV) as a prognostic indicator in invasive squamous cell carcinoma of the uterine cervix.

STUDY DESIGN:

Forty-nine consecutive cases of invasive squamous cell carcinoma of the cervix diagnosed in 1995 were analyzed retrospectively for MNV and correlated with outcome at the end of a 5-year follow-up period.

RESULTS:

The average MNV among patients with a 5-year disease-free survival (DFS) and patients with disease recurrence within the same period was 1424.11 microm3 and 1401.49 microm3, respectively (P = .984, Mann-Whitney test), indicating a poor relationship between MNV and 5-year DFS.

CONCLUSION:

Estimation of MNV alone in cases of invasive squamous cell carcinoma of the cervix is not predictive of DFS.

PMID:
15457676
[Indexed for MEDLINE]
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