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Med J Aust. 1992 Mar 16;156(6):413-6.

Alcohol consumption and the risk of cirrhosis.

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1
Drug and Alcohol Unit, Westmead Hospital, NSW.

Abstract

OBJECTIVE:

To determine risk levels for the development of cirrhosis in Australian men who consume alcohol and to compare this risk with that of Australian women.

DESIGN AND SETTING:

A case-control study using an interview technique, based in two major tertiary referral hospitals in Sydney.

PATIENTS:

Forty-three men with newly diagnosed cirrhosis of the liver and a total of 115 male control subjects, age matched with the case subjects. The data for women (36 cases and 99 controls) have been reported previously.

RESULTS:

The risk of men developing cirrhosis increases significantly above the baseline when the alcohol intake exceeds 40 g per day. The risk to women is significant at a similar intake level. Dietary intake and past major illnesses appear to have no role in determining risk.

CONCLUSION:

The recommended safe drinking level for men and women should be 40 g per day, as suggested by the National Health and Medical Research Council.

PMID:
1545749
[Indexed for MEDLINE]
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