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Bull Exp Biol Med. 2004 May;137(5):471-4.

Effect of baikal skullcap extract administered alone or in combination with cyclophosphamide on natural cytotoxicity system in mice with Lewis lung carcinoma.

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Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk.


Baikal skullcap extract was introduced into cytostatic therapy of mice with Lewis lung carcinoma. This extract potentiated the antimetastatic effect of cyclophosphamide in mice with grafted tumors. Combined treatment with cyclophosphamide and extract of Baikal skullcap modulated cytotoxic activity of natural killer cells and peritoneal macrophages during tumor growth.

[Indexed for MEDLINE]

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