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Hematol J. 2004;5(5):373-80.

The molecular regulation of iron metabolism.

Author information

1
Department of Pediatrics, Division of Hematology/Oncology, Howard Hughes Medical Institute, Harvard Medical School, Children's Hospital, Boston, MA 02115-5737, USA.

Abstract

Mammalian iron homeostasis requires meticulous control of proteins involved in intestinal iron absorption and tissue iron management. Recent studies in animal models have provided important insights into iron physiology. This review describes our current understanding of the regulation of iron trafficking and its perturbation in genetic iron disorders.

PMID:
15448662
DOI:
10.1038/sj.thj.6200540
[Indexed for MEDLINE]

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