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Nature. 1992 Feb 13;355(6361):601-4.

Crisscross regulation of cell-type-specific gene expression during development in B. subtilis.

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1
Department of Cellular and Developmental Biology, Harvard University, Cambridge, Massachusetts 02138.

Abstract

Sporulation in Bacillus subtilis is a model for how cells of one type generate other differentiated cell types. During sporulation two cellular compartments arise that differ from each other and from the progenitor cell. Differential gene expression between the two is governed by the successive appearance of four transcription factors whose activities are coordinated in crisscross fashion between the two cells.

PMID:
1538747
DOI:
10.1038/355601a0
[Indexed for MEDLINE]
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