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Jpn Circ J. 1992 Jan;56(1):95-9.

Usefulness of taurine in chronic congestive heart failure and its prospective application.

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Third Department of Internal Medicine, Osaka University Medical School, Japan.


We compared the effect of oral administration of taurine (3 g/day) and coenzyme Q10 (CoQ10) (30 mg/day) in 17 patients with congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy, whose ejection fraction assessed by echocardiography was less than 50%. The changes in echocardiographic parameters produced by 6 weeks of treatment were evaluated in a double-blind fashion. In the taurine-treated group significant treatment effect was observed on systolic left ventricular function after 6 weeks. Such an effect was not observed in the CoQ10-treated group.

[Indexed for MEDLINE]

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