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Nat Rev Microbiol. 2004 Sep;2(9):721-6.

Antitoxins: novel strategies to target agents of bioterrorism.

Author information

1
Infectious Disease Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037-1099, USA.

Abstract

Never before has there been such a strong possibility that biological agents might be used indiscriminately on civilian populations. This review focuses on the use of antitoxins - antibodies, receptor decoys, dominant-negative inhibitors of translocation, small-molecule inhibitors and substrate analogues - to counteract those biological weapons for which toxins are an important mechanism of disease pathogenesis.

PMID:
15372082
DOI:
10.1038/nrmicro977
[Indexed for MEDLINE]

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