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J Clin Microbiol. 2004 Sep;42(9):4332-4.

Multicenter validation of the cppB gene as a PCR target for detection of Neisseria gonorrhoeae.

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1
GG&GD Municipal Health Service, Public Health Laboratory, Nieuwe Achtergracht 100, 1018 WT Amsterdam, The Netherlands. sbruisten@gggd.amsterdam.nl

Abstract

The cppB gene is often used as a target for detection of Neisseria gonorrhoeae by PCR. Using a coded panel of 500 DNA samples, we determined that the cppB gene is missing in 5.8% of N. gonorrhoeae strains, and therefore we consider the cppB gene to be an unsuitable target.

PMID:
15365038
PMCID:
PMC516305
DOI:
10.1128/JCM.42.9.4332-4334.2004
[Indexed for MEDLINE]
Free PMC Article
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