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Trends Genet. 2004 Oct;20(10):461-4.

Genome duplication led to highly selective expansion of the Arabidopsis thaliana proteome.

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1
South African National Bioinformatics Institute, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africa. cathal@science.uct.ac.za

Abstract

Multiple ancient genome duplications in Arabidopsis thaliana provide unique opportunities to assess factors that influence the fates of duplicated genes. We have found that genes retained in duplicate following one round of genome duplication are significantly more likely to be retained in duplicate again after a subsequent genome duplication. Genes retained in duplicate form a functionally biased set and include a significant over-representation of genes involved in the regulation of transcription.

PMID:
15363896
DOI:
10.1016/j.tig.2004.07.008
[Indexed for MEDLINE]
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