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Dev Cell. 2004 Sep;7(3):301-12.

Segmentation.

Author information

1
Institut für Genetik der Universität zu Köln, Weyertal 121, 50931, Germany. tautz@uni-koeln.de

Abstract

The three major taxa with metameric segmentation (annelids, arthropods, and chordates) appear to use three very different molecular strategies to generate segments. However, unexpected similarities are starting to emerge from characterization of pair-rule patterning and segmental border formation. Moreover, the existence of an ancestral segmentation clock based on Notch signaling has become likely. An old concept of comparative anatomy, the enterocoele theory, is compatible with a single origin of segmentation mechanisms and could therefore provide a conceptual framework for assessing these molecular similarities.

PMID:
15363406
DOI:
10.1016/j.devcel.2004.08.008
[Indexed for MEDLINE]
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