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J Proteome Res. 2004 Jul-Aug;3(4):878-83.

Analysis of altered protein expression patterns of Chlamydia pneumoniae by an integrated proteome-works system.

Author information

1
Division of Infectious Diseases, University of Louisville, Louisville, Kentucky 40292, USA.

Abstract

We have identified, analyzed, and quantified differential protein expression profile of five C. pneumoniae proteins, Adk (adenylate kinase), AhpC (thiol-specific antioxidant), CrpA (15 KD cysteine rich protein), Map (methionine aminopeptidae), and Cpn0710 (hypothetical protein) under normal versus persistent growth conditions induced by interferon-gamma, at different time intervals of their replicative cycle by successfully employing the latest proteomic analysis tool, PDQuest 2-D analysis software. We have also determined that this software represents a reliable analytical tool for mapping protein expression patterns in C. pneumoniae.

PMID:
15359744
[Indexed for MEDLINE]

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