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J Neuroimaging. 2004 Oct;14(4):369-71.

Reversible cerebellar lesions induced by metronidazole therapy for helicobacter pylori.

Author information

1
Division of Neurology, Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan. sipin@med.toho-u.ac.jp

Abstract

Metronidazole is widely used for chronic or refractory infection and has recently also been used for the treatment of Helicobacter pylori. The authors report the case of a Japanese patient presenting with reversible cerebellar lesions induced by prolonged administration of metronidazole for treatment of H pylori with magnetic resonance imaging findings. Although rare, prolonged and high-dose administration of metronidazole may induce cerebellar lesions. Increased awareness of this phenomenon is important, as these lesions are reversible with discontinuation of this drug.

PMID:
15358960
DOI:
10.1177/1051228404267597
[Indexed for MEDLINE]

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