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Fitoterapia. 2004 Sep;75(6):557-65.

Antiinflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare.

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Department of Biotechnology and Bioproducts Research Center, Yonsei University, 330-326, Hongjae-dong, Seodaemun-gu, Seoul 120-091, South Korea.


Oral administration (200 mg/kg) of Foeniculum vulgare fruit methanolic extract exhibited inhibitory effects against acute and subacute inflammatory diseases and type IV allergic reactions and showed a central analgesic effect. Moreover, it significantly increased the plasma superoxide dismutase (SOD) and catalase activities and the high density lipoprotein-cholesterol level. On the contrary, the malondialdehyde (MDA) (as a measure of lipid peroxidation) level was significantly decreased in F. vulgare fruit methanolic extract group compared to the control group (P<0.05). These results seems to support the use of F. vulgare fruit methanolic extract in relieving inflammation.

[Indexed for MEDLINE]

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