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Dermatol Online J. 2004 Jul 15;10(1):12.

Colocalized nevus depigmentosus and lentigines with underlying breast hypoplasia: a case of reverse mutation?

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  • 1Department of Dermatology, Lady Hardinge Medical College and Associated SSK and KSC Hospitals, New Delhi, India.


Nevus depigmentosus (ND) is classically defined as a congenital nonprogressive hypopigmented macule, stable in size and distribution. There have been many reports of colocalization of ND and lentigines. We describe development of multiple lentigines over ND in a 9-year-old girl along with hypoplasia of the underlying breast. The case is being reported to highlight the phenotypic manifestation of reverse mutation and the coincidental breast hypoplasia that has not been reported before.

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